1. hit the 'add region' button to create a new region
2. note the region name
3. position it appropriately
4. repeat for your entire screen
5. if you have multiple screens, use the display selector to go to the other screens layout
6. check 'enable maximizer' when done

Now you need to define a command
--
keyclone/setup/command editor

1. assuming you have no commands created, type a command name into the 'command name' field.
2. click the 'program...' button (make sure to select WoW.exe and NOT launcher.exe)
2a. if you selected wow.exe, the wow:username field should be enabled
2b. on vista, you are looking for the wow application.. NOT launcher
3. fill in the region name (exactly as typed in the maximizer)
4. check the wow:username
5. fill in the wow:username
6. set the maxfpsbk and maxfps
7. hit the 'add command' button
8. repeat for each command

now tweak the general settings
--
keyclone/setup/general

1. UNCHECK 'auto-add windows' field
2. make sure 'pass mouse clicks' is UNCHECKED
3. CHECK the 'focus follows mouse' option
4. CHECK the startup command
4a. command can be single or multiple commands
5. set the time delay after startup to trigger the commands
6. if you are using multiple keyclones, put in the ip and port of the remote keyclone

Results...

if you did it right, a single command will generate a screen that could look like this: